Randy Mosiondz: In Neverwinter we usually try to parallel a lot of the Forgotten Realms story development that Wizards of the Coast has been doing over the last few years. At launch, the majority of our adventure zones were based on stories were being told in the Realms, primarily focusing on Valindra, the Crown of Neverwinter, Gauntlgrym, and the aftermath of the Spellplague. One of our main sources of inspiration was the D&D 4th edition Neverwinter Campaign Guide, which had a number of great story seeds.
We did add a number of new zones that were not directly connected to that book but were still drawn from Realms lore. In a lot of these cases we simply wanted to make sure there was enough variety in storylines, environments, and monsters you encountered to ensure we covered all of the high points of the D&D adventuring experience. Whenever we do this, we consult with Wizards of the Coast on a weekly basis to ensure these storylines match up to their expectations of what fits in the Forgotten Realms.